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DNA Replication Quiz — Grade 11–12 | 20 Multiple Choice Questions with Answers

Test your understanding of DNA replication with this 20-question multiple choice quiz for Grade 11–12 biology students. This quiz covers enzymes, base pairing, leading and lagging strands, and replication processes. Perfect for high school…

20 questions
10 min
Intermediate
Grade 12
DNA Replication Quiz — Grade 11–12 | 20 Multiple Choice Questions with Answers
Test your understanding of DNA replication with this 20-question multiple choice quiz for Grade 11–12 biology students. This quiz covers enzymes, base pairing, leading and lagging strands, and…
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Test your understanding of DNA replication with this 20-question multiple choice quiz for Grade 11–12 biology students. This quiz covers enzymes, base pairing, leading and lagging strands, and replication processes. Perfect for high school biology review and exam preparation.

DNA Replication Quiz — Grade 11–12 | 20 Multiple Choice Questions with Answers

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Questions in this quiz

  1. DNA replication occurs in which part of the cell?
    • A. Cytoplasm
    • B. Ribosome
    • C. Nucleus
    • D. Cell membrane
  2. DNA replication occurs during which phase of the cell cycle?
    • A. G1 Phase
    • B. S Phase
    • C. G2 Phase
    • D. M Phase
  3. Which enzyme unwinds the DNA double helix?
    • A. DNA polymerase
    • B. Helicase
    • C. Ligase
    • D. Primase
  4. Which enzyme adds new nucleotides to the growing DNA strand?
    • A. Helicase
    • B. Ligase
    • C. DNA polymerase
    • D. RNA polymerase
  5. DNA replication is described as:
    • A. Conservative
    • B. Semi-conservative
    • C. Dispersive
    • D. Random
  6. Which bases pair together in DNA?
    • A. A–G, C–T
    • B. A–T, C–G
    • C. A–C, T–G
    • D. A–A, T–T
  7. The short DNA fragments on the lagging strand are called:
    • A. Replication forks
    • B. Okazaki fragments
    • C. Primers
    • D. Codons
  8. Which enzyme joins Okazaki fragments?
    • A. Helicase
    • B. DNA polymerase
    • C. Ligase
    • D. Primase
  9. The strand that is synthesized continuously is called:
    • A. Lagging strand
    • B. Leading strand
    • C. Template strand
    • D. Coding strand
  10. DNA replication begins at the:
    • A. Replication fork
    • B. Origin of replication
    • C. Centromere
    • D. Codon
  11. Which direction does DNA polymerase build new DNA?
    • A. 3' to 5'
    • B. 5' to 3'
    • C. Both directions
    • D. Random direction
  12. RNA primers are added by which enzyme?
    • A. Ligase
    • B. Primase
    • C. Helicase
    • D. Polymerase
  13. DNA replication produces:
    • A. One DNA molecule
    • B. Two identical DNA molecules
    • C. Three DNA molecules
    • D. Four DNA molecules
  14. Which strand is synthesized in fragments?
    • A. Leading strand
    • B. Lagging strand
    • C. Template strand
    • D. Coding strand
  15. The shape of DNA is called:
    • A. Double strand
    • B. Double helix
    • C. Double chain
    • D. Spiral chain
  16. Which base pairs with adenine?
    • A. Cytosine
    • B. Guanine
    • C. Thymine
    • D. Uracil
  17. Which base pairs with cytosine?
    • A. Adenine
    • B. Guanine
    • C. Thymine
    • D. Uracil
  18. What holds DNA strands together?
    • A. Ionic bonds
    • B. Hydrogen bonds
    • C. Peptide bonds
    • D. Metallic bonds
  19. DNA replication ensures:
    • A. Energy production
    • B. Genetic information is copied
    • C. Proteins are made
    • D. Cells divide immediately
  20. Replication forks form when:
    • A. DNA strands separate
    • B. DNA strands combine
    • C. Proteins form
    • D. RNA forms
Show answer key
Answer key — DNA Replication Quiz — Grade 11–12 | 20 Multiple Choice Questions with Answers
  1. 1. C
  2. 2. B
  3. 3. B
  4. 4. C
  5. 5. B
  6. 6. B
  7. 7. B
  8. 8. C
  9. 9. B
  10. 10. B
  11. 11. B
  12. 12. B
  13. 13. B
  14. 14. B
  15. 15. B
  16. 16. C
  17. 17. B
  18. 18. B
  19. 19. B
  20. 20. A
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